For the first time, scientists have announced the genetic modification of human embryos (germline modification), in a study conducted by researchers from Sun Yat-sen University in Guangzhou, China, and published in the journal Protein & Cell.
The researchers sought to modify the gene responsible for a potentially fatal blood disorder known as s-thalassaemia. They used a gene editing technique called CRISPR/Cas9, which has been successfully used to modify the genomes of adult cells in the past. The technique consists of injecting the target cells with the CRISPR/Cas9 enzyme complex, programmed to target (remove) a specific gene. At the same time, another molecule is injected which is programmed to insert a new gene in place of the removed ones.
The researchers injected 86 single-celled human embryos with the molecules, then waited 48 hours for them to multiply into about eight cells each. Only 71 embryos survived the process, and only 54 of these were genetically tested. The original gene was successfully removed in only 24, and in only a few of these did the replacement gene take root.
“If you want to do it in normal embryos, you need to be close to 100 percent,” lead researcher Junjiu Huang said. “That’s why we stopped. We still think it’s too immature.”
The paper was preceded for months by rumors, which led to a March editorial in the journal Nature, calling for a moratorium on germline modification.
Existing gene therapies modify genes only in adult cells, and therefore are more limited in their effects. This may restore certain functions to a damaged organ, for instance, but is less likely to cause major changes to other types of cells than germline modification.
In contrast, a fertilized egg (zygote) eventually multiplies and differentiates into every cell in the adult organism. Modifying the genome of this cell causes changes in the organism-wide genome, and can potentially change the function of every organ in the body. In addition, such changes are passed on to future generations, by definition without their consent. It is also impossible to fully understand the long-term effects these modifications could have, across the generations.
Any germline modification, many ethicists have also warned, opens up a slippery slope toward attempts to “improve” the human genome, such as the creation of “designer babies.” The uses of germline modification are so potentially broad, that the risk of unethical uses is enormous.
Other germline modification studies, however, are already underway elsewhere in China.
TO BE FOREWARNED IS TO BE FOREARMED FOR SUCH A TIME AS THIS! I warned what would happen in MY Word when mankind would play GOD for that is all they can do is play. They don’t understand for this they will pay as they seek to become a GOD a creator, This GOD of Creation is going to show them for I will take the very knowledge given to them and turn it against them.
TO BE FOREWARNED IS TO BE FOREARMED FOR SUCH A TIME AS THIS! Be warned when mankind is cloned, they are born without a soul and any creation without a soul is a dangerous thing.For mankind is meant to have a soul, I breathed the breath of life into Adam, but when mankind creates clones of Adam, and Eve, I tell you this there will be no breath of life in them. Instead it will be the breath of the soulless one, satan will be the father and evil will be the reward for playing God. These clones will not have the lifespan as MY creation, nor the desire to serve and worship the GOD ‘I AM’! These clones will not have a conscience for ‘I AM’ mankind’s conscience of what is right and wrong. These clones will turn on the very creators and on mankind that allows such heinous creatures.
It is I, YAHUVEH, I will have the last laugh. You have aroused MY ire, you have aroused MY wrath. You say, “I will play GOD” with the knowledge I have given you. You create man in man’s own image, when MY Word says you were created in MY image. You play your games with the weather. Now I shall show you the creator of that weather. Your own clones shall turn against you. Your own inventions shall turn against you. Any weapon that you try and use against MY Children shall boomerang back upon you. For I am judging Sodom and Gomorrah again, I am looking over the face of this world. I know which ones MY angels have sealed and these things shall not befall them.